Legomedicine—A Versatile Chemo-Enzymatic Approach for the Preparation of Targeted Dual-Labeled Llama Antibody–Nanoparticle Conjugates

[Image: see text] Conjugation of llama single domain antibody fragments (Variable Heavy chain domains of Heavy chain antibodies, VHHs) to diagnostic or therapeutic nanoparticles, peptides, proteins, or drugs offers many opportunities for optimized targeted cancer treatment. Currently, mostly nonspec...

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Detalles Bibliográficos
Autores principales: van Lith, Sanne A. M., van Duijnhoven, Sander M. J., Navis, Anna C., Leenders, William P. J., Dolk, Edward, Wennink, Jos W. H., van Nostrum, Cornelus F., van Hest, Jan C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330650/
https://www.ncbi.nlm.nih.gov/pubmed/28045502
http://dx.doi.org/10.1021/acs.bioconjchem.6b00638

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