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Modelling primaquine-induced haemolysis in G6PD deficiency

Primaquine is the only drug available to prevent relapse in vivax malaria. The main adverse effect of primaquine is erythrocyte age and dose-dependent acute haemolytic anaemia in individuals with glucose-6-phosphate dehydrogenase deficiency (G6PDd). As testing for G6PDd is often unavailable, this li...

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Detalles Bibliográficos
Autores principales:	Watson, James, Taylor, Walter RJ, Menard, Didier, Kheng, Sim, White, Nicholas J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Computational and Systems Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330681/ https://www.ncbi.nlm.nih.gov/pubmed/28155819 http://dx.doi.org/10.7554/eLife.23061

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