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The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression
The mechanisms underlying the neurodevelopmental deficits associated with CHARGE syndrome, which include cerebellar hypoplasia, developmental delay, coordination problems, and autistic features, have not been identified. CHARGE syndrome has been associated with mutations in the gene encoding the ATP...
Autores principales: | Whittaker, Danielle E., Riegman, Kimberley L.H., Kasah, Sahrunizam, Mohan, Conor, Yu, Tian, Sala, Blanca Pijuan, Hebaishi, Husam, Caruso, Angela, Marques, Ana Claudia, Michetti, Caterina, Smachetti, María Eugenia Sanz, Shah, Apar, Sabbioni, Mara, Kulhanci, Omer, Tee, Wee-Wei, Reinberg, Danny, Scattoni, Maria Luisa, Volk, Holger, McGonnell, Imelda, Wardle, Fiona C., Fernandes, Cathy, Basson, M. Albert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330721/ https://www.ncbi.nlm.nih.gov/pubmed/28165338 http://dx.doi.org/10.1172/JCI83408 |
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