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Molecular Analysis of Factor VIII and Factor IX Genes in Hemophilia Patients: Identification of Novel Mutations and Molecular Dynamics Studies
BACKGROUND: Hemophilias A and B are X-linked bleeding disorders caused by mutations in the factor VIII and factor IX genes, respectively. Our objective was to identify the spectrum of mutations of the factor VIII and factor IX genes in Saudi Arabian population and determine the genotype and phenotyp...
Autores principales: | Al-Allaf, Faisal A., Taher, Mohiuddin M., Abduljaleel, Zainularifeen, Bouazzaoui, Abdellatif, Athar, Mohammed, Bogari, Neda M., Abalkhail, Halah A., Owaidah, Tarek MA. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elmer Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330775/ https://www.ncbi.nlm.nih.gov/pubmed/28270892 http://dx.doi.org/10.14740/jocmr2876w |
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