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Massively multiplex single-cell Hi-C
We present single-cell combinatorial indexed Hi-C (sciHi-C), which applies the concept of combinatorial cellular indexing to chromosome conformation capture. In this proof-of-concept, we generate and sequence six sciHi-C libraries comprising a total of 10,696 single cells. We use sciHi-C data to sep...
Autores principales: | Ramani, Vijay, Deng, Xinxian, Qiu, Ruolan, Gunderson, Kevin L, Steemers, Frank J, Disteche, Christine M, Noble, William S, Duan, Zhijun, Shendure, Jay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330809/ https://www.ncbi.nlm.nih.gov/pubmed/28135255 http://dx.doi.org/10.1038/nmeth.4155 |
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