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Characterizing cell subsets in heterogeneous tissues using marker enrichment modeling
Learning cell identity from single-cell data presently relies on human experts. Here, we present Marker Enrichment Modeling (MEM), an algorithm that objectively describes cells by quantifying contextual feature enrichment and reporting a human and machine-readable text label. MEM outperformed tradit...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330853/ https://www.ncbi.nlm.nih.gov/pubmed/28135256 http://dx.doi.org/10.1038/nmeth.4149 |