Cargando…

Targeting Multidrug-resistant Staphylococci with an anti-rpoA Peptide Nucleic Acid Conjugated to the HIV-1 TAT Cell Penetrating Peptide

Staphylococcus aureus infections present a serious challenge to healthcare practitioners due to the emergence of resistance to numerous conventional antibiotics. Due to their unique mode of action, peptide nucleic acids are novel alternatives to traditional antibiotics to tackle the issue of bacteri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abushahba, Mostafa FN, Mohammad, Haroon, Seleem, Mohamed N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330942/ https://www.ncbi.nlm.nih.gov/pubmed/27434684 http://dx.doi.org/10.1038/mtna.2016.53

Ejemplares similares

Impact of different cell penetrating peptides on the efficacy of antisense therapeutics for targeting intracellular pathogens
por: Abushahba, Mostafa F. N., et al.
Publicado: (2016)

Cell-penetrating peptide conjugates of peptide nucleic acids (PNA) as inhibitors of HIV-1 Tat-dependent trans-activation in cells
por: Turner, John J., et al.
Publicado: (2005)

Synonymous Mutations in rpsT Lead to Ribosomal Assembly Defects That Can Be Compensated by Mutations in fis and rpoA
por: Knöppel, Anna, et al.
Publicado: (2020)

New Evolutionary Insights into RpoA: A Novel Quorum Sensing Reprograming Factor in Pseudomonas aeruginosa
por: Cai, Wenjie, et al.
Publicado: (2023)

Conjugation to the Cell-Penetrating Peptide TAT Potentiates the Photodynamic Effect of Carboxytetramethylrhodamine
por: Srinivasan, Divyamani, et al.
Publicado: (2011)

Delivery of cell-penetrating peptide-peptide nucleic acid conjugates by assembly on an oligonucleotide scaffold
por: Zhao, Xing-Liang, et al.
Publicado: (2015)

Cell Penetrating Peptide Conjugated Chitosan for Enhanced Delivery of Nucleic Acid
por: Layek, Buddhadev, et al.
Publicado: (2015)

Cell-Penetrating Peptide–Peptide Nucleic Acid Conjugates as a Tool for Protein Functional Elucidation in the Native Bacterium
por: Yokoi, Yasuhito, et al.
Publicado: (2022)

Delivery of Antisense Peptide Nucleic Acids to Cells by Conjugation with Small Arginine-Rich Cell-Penetrating Peptide (R/W)9
por: Cordier, Céline, et al.
Publicado: (2014)

Fluorescent and Photosensitizing Conjugates of Cell-Penetrating Peptide TAT(47-57): Design, Microwave-Assisted Synthesis at 60 °C, and Properties
por: Okuda-Shinagawa, Nancy M., et al.
Publicado: (2017)

Conjugation of Therapeutic PSD-95 Inhibitors to the Cell-Penetrating Peptide Tat Affects Blood–Brain Barrier Adherence, Uptake, and Permeation
por: Kristensen, Mie, et al.
Publicado: (2020)

Synthesis, cellular uptake and HIV-1 Tat-dependent trans-activation inhibition activity of oligonucleotide analogues disulphide-conjugated to cell-penetrating peptides
por: Turner, John J., et al.
Publicado: (2005)

A Tat-conjugated Peptide Nucleic Acid Tat-PNA-DR Inhibits Hepatitis B Virus Replication In Vitro and In Vivo by Targeting LTR Direct Repeats of HBV RNA
por: Zeng, Zhengyang, et al.
Publicado: (2016)

Depicting Binding-Mediated Translocation of HIV-1 Tat Peptides in Living Cells with Nanoscale Pens of Tat-Conjugated Quantum Dots
por: Lin, Chien Y., et al.
Publicado: (2017)

A short D-enantiomeric antimicrobial peptide with potent immunomodulatory and antibiofilm activity against multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii
por: Mohamed, Mohamed F., et al.
Publicado: (2017)

A nuclear-encoded protein, mTERF6, mediates transcription termination of rpoA polycistron for plastid-encoded RNA polymerase-dependent chloroplast gene expression and chloroplast development
por: Zhang, Yi, et al.
Publicado: (2018)

Conjugation of Cell-Penetrating Peptides to Antimicrobial Peptides Enhances Antibacterial Activity
por: Lee, Hyunhee, et al.
Publicado: (2019)

Examining the Cellular Transport Pathway of Fusogenic Quantum Dots Conjugated With Tat Peptide
por: Dai, Jie, et al.
Publicado: (2022)

An Efficient Approach for the Design and Synthesis of Antimicrobial Peptide-Peptide Nucleic Acid Conjugates
por: Patil, Nitin A., et al.
Publicado: (2022)

Self-Assembly of Diphenylalanine–Peptide Nucleic Acid Conjugates
por: Datta, Dhrubajyoti, et al.
Publicado: (2019)

Effects of the properties of short peptides conjugated with cell-penetrating peptides on their internalization into cells
por: Matsumoto, Ryo, et al.
Publicado: (2015)

Role of Cell-Penetrating Peptides in Intracellular Delivery of Peptide Nucleic Acids Targeting Hepadnaviral Replication
por: Ndeboko, Bénédicte, et al.
Publicado: (2017)

Comparative Immunogenicity of a Cytotoxic T Cell Epitope Delivered by Penetratin and TAT Cell Penetrating Peptides
por: Brooks, Nicole, et al.
Publicado: (2015)

Photodynamic therapy by conjugation of cell-penetrating peptide with fluorochrome
por: Park, Chul-Kyu, et al.
Publicado: (2017)

Cell penetrating peptide conjugates of steric block oligonucleotides()
por: Lebleu, Bernard, et al.
Publicado: (2008)

Antimicrobial and Cell-Penetrating Peptides: Understanding Penetration for the Design of Novel Conjugate Antibiotics
por: Hadjicharalambous, Andreas, et al.
Publicado: (2022)

Delivery of Nucleic Acids and Nanomaterials by Cell-Penetrating Peptides: Opportunities and Challenges
por: Huang, Yue-Wern, et al.
Publicado: (2015)

A branched TAT cell-penetrating peptide as a novel delivery carrier for the efficient gene transfection
por: Jeong, Chanuk, et al.
Publicado: (2016)

Therapeutic effects, immunogenicity and cytotoxicity of a cell penetrating peptide-peptide nucleic acid conjugate against cagA of Helicobacter pylori in cell culture and animal model
por: Farahani, Narges Nodeh, et al.
Publicado: (2021)

Molecular Dynamics Simulations of Drug-Conjugated Cell-Penetrating Peptides
por: Ivánczi, Márton, et al.
Publicado: (2023)

Peptide Nucleic Acid–Fluorescence In Situ Hybridization for Detection of Staphylococci From Endophthalmitis Isolates: A Proof-of-Concept Study
por: Patel, Nimesh, et al.
Publicado: (2017)

Efficient cell penetration and delivery of peptide nucleic acids by an argininocalix[4]arene
por: Gasparello, Jessica, et al.
Publicado: (2019)

Comparing Variants of the Cell-Penetrating Peptide sC18 to Design Peptide-Drug Conjugates
por: Grabeck, Joshua, et al.
Publicado: (2022)

Effect of a Fusion Peptide by Covalent Conjugation of a Mitochondrial Cell-Penetrating Peptide and a Glutathione Analog Peptide
por: Cerrato, Carmine Pasquale, et al.
Publicado: (2017)

Synergistic Enhancement of Antitumor Efficacy by PEGylated Multi-walled Carbon Nanotubes Modified with Cell-Penetrating Peptide TAT
por: Hu, Shanshan, et al.
Publicado: (2016)

Introduction of multiphosphonate ligand to peptide nucleic acid for metal ion conjugation
por: Aiba, Yuichiro, et al.
Publicado: (2012)

Peptide nucleic acid conjugates and their antimicrobial applications—a mini-review
por: Tsylents, Uladzislava, et al.
Publicado: (2023)

Developments in Cell-Penetrating Peptides as Antiviral Agents and as Vehicles for Delivery of Peptide Nucleic Acid Targeting Hepadnaviral Replication Pathway
por: Ndeboko, Bénédicte, et al.
Publicado: (2018)

Dynamic interactions of the HIV-1 Tat with nucleic acids are critical for Tat activity in reverse transcription
por: Boudier, Christian, et al.
Publicado: (2014)

Mitochondria-penetrating peptides conjugated to desferrioxamine as chelators for mitochondrial labile iron
por: Alta, Roxana Y. P., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_mg4o3faaga9cn5cpt7258dva00