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Immunostimulated Arginase II Expression in Intestinal Epithelial Cells Reduces Nitric Oxide Production and Apoptosis

Increased production of nitric oxide (NO) and subsequent local cytotoxicity to mucosal epithelial cells has been proposed as a putative mechanism involved in the development of necrotizing enterocolitis (NEC). Intestinal epithelial cells (IECs) metabolize L-arginine to either nitric oxide (NO) by NO...

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Detalles Bibliográficos
Autores principales: Talavera, Maria M., Nuthakki, Sushma, Cui, Hongmei, Jin, Yi, Liu, Yusen, Nelin, Leif D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331049/
https://www.ncbi.nlm.nih.gov/pubmed/28299311
http://dx.doi.org/10.3389/fcell.2017.00015