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L‐OPA1 regulates mitoflash biogenesis independently from membrane fusion
Mitochondrial flashes mediated by optic atrophy 1 (OPA1) fusion protein are bioenergetic responses to stochastic drops in mitochondrial membrane potential (Δψ(m)) whose origin is unclear. Using structurally distinct genetically encoded pH‐sensitive probes, we confirm that flashes are matrix alkalini...
Autores principales: | Rosselin, Manon, Santo‐Domingo, Jaime, Bermont, Flavien, Giacomello, Marta, Demaurex, Nicolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331265/ https://www.ncbi.nlm.nih.gov/pubmed/28174208 http://dx.doi.org/10.15252/embr.201642931 |
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