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L‐OPA1 regulates mitoflash biogenesis independently from membrane fusion

Mitochondrial flashes mediated by optic atrophy 1 (OPA1) fusion protein are bioenergetic responses to stochastic drops in mitochondrial membrane potential (Δψ(m)) whose origin is unclear. Using structurally distinct genetically encoded pH‐sensitive probes, we confirm that flashes are matrix alkalini...

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Detalles Bibliográficos
Autores principales: Rosselin, Manon, Santo‐Domingo, Jaime, Bermont, Flavien, Giacomello, Marta, Demaurex, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331265/
https://www.ncbi.nlm.nih.gov/pubmed/28174208
http://dx.doi.org/10.15252/embr.201642931

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