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The Combination of MBP and BCG-Induced Dendritic Cell Maturation through TLR2/TLR4 Promotes Th1 Activation In Vitro and Vivo
To explore whether TLR2/TLR4 could be involved in the maturation of dendritic cells and polarization of CD4(+) T cells induced by dendritic cells stimulated with MBP and BCG, in vitro and in vivo experiments using TLR2(−/−) or TLR4(−/−) mice were employed. MBP and BCG elevated CD80, CD86 and MHC cla...
Autores principales: | Jiang, LiNa, Liu, GuoMu, Ni, WeiHua, Zhang, NanNan, Jie, Jing, Xie, Fei, Tai, GuiXiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331320/ https://www.ncbi.nlm.nih.gov/pubmed/28293065 http://dx.doi.org/10.1155/2017/1953680 |
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