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Protection against Shiga Toxins

Shiga toxins consist of an A-moiety and five B-moieties able to bind the neutral glycosphingolipid globotriaosylceramide (Gb3) on the cell surface. To intoxicate cells efficiently, the toxin A-moiety has to be cleaved by furin and transported retrogradely to the Golgi apparatus and to the endoplasmi...

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Detalles Bibliográficos
Autores principales:	Kavaliauskiene, Simona, Dyve Lingelem, Anne Berit, Skotland, Tore, Sandvig, Kirsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331424/ https://www.ncbi.nlm.nih.gov/pubmed/28165371 http://dx.doi.org/10.3390/toxins9020044

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