Speeding up enzyme engineering computationally

Can in silico engineering speed up the delivery of biocatalysts for the burgeoning bioeconomy? In this issue, Kamerlin and coworkers introduce CADEE [Amrein et al. (2017), IUCrJ, 4, 50–64] – a framework for Computer-Aided Directed Evolution of Enzymes – that promises to lessen the burden on ‘wet lab...

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Detalles Bibliográficos
Autor principal: Scrutton, Nigel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2016
Materias:
Scientific Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331461/
https://www.ncbi.nlm.nih.gov/pubmed/28250937
http://dx.doi.org/10.1107/S2052252516019692
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author Scrutton, Nigel S.
author_facet Scrutton, Nigel S.
author_sort Scrutton, Nigel S.
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description Can in silico engineering speed up the delivery of biocatalysts for the burgeoning bioeconomy? In this issue, Kamerlin and coworkers introduce CADEE [Amrein et al. (2017), IUCrJ, 4, 50–64] – a framework for Computer-Aided Directed Evolution of Enzymes – that promises to lessen the burden on ‘wet lab’ enzymologists when optimizing biocatalysts using laboratory-based directed evolution methods.
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spelling pubmed-53314612017-03-01 Speeding up enzyme engineering computationally Scrutton, Nigel S. IUCrJ Scientific Commentaries Can in silico engineering speed up the delivery of biocatalysts for the burgeoning bioeconomy? In this issue, Kamerlin and coworkers introduce CADEE [Amrein et al. (2017), IUCrJ, 4, 50–64] – a framework for Computer-Aided Directed Evolution of Enzymes – that promises to lessen the burden on ‘wet lab’ enzymologists when optimizing biocatalysts using laboratory-based directed evolution methods. International Union of Crystallography 2016-12-24 /pmc/articles/PMC5331461/ /pubmed/28250937 http://dx.doi.org/10.1107/S2052252516019692 Text en © Nigel S. Scrutton 2017 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.http://creativecommons.org/licenses/by/2.0/uk/
spellingShingle Scientific Commentaries
Scrutton, Nigel S.
Speeding up enzyme engineering computationally
title Speeding up enzyme engineering computationally
title_full Speeding up enzyme engineering computationally
title_fullStr Speeding up enzyme engineering computationally
title_full_unstemmed Speeding up enzyme engineering computationally
title_short Speeding up enzyme engineering computationally
title_sort speeding up enzyme engineering computationally
topic Scientific Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331461/
https://www.ncbi.nlm.nih.gov/pubmed/28250937
http://dx.doi.org/10.1107/S2052252516019692
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