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Mutation of Tyr137 of the universal Escherichia coli fimbrial adhesin FimH relaxes the tyrosine gate prior to mannose binding

The most prevalent diseases manifested by Escherichia coli are acute and recurrent bladder infections and chronic inflammatory bowel diseases such as Crohn’s disease. E. coli clinical isolates express the FimH adhesin, which consists of a mannose-specific lectin domain connected via a pilin domain t...

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Detalles Bibliográficos
Autores principales:	Rabbani, Said, Krammer, Eva-Maria, Roos, Goedele, Zalewski, Adam, Preston, Roland, Eid, Sameh, Zihlmann, Pascal, Prévost, Martine, Lensink, Marc F., Thompson, Andrew, Ernst, Beat, Bouckaert, Julie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2017
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331462/ https://www.ncbi.nlm.nih.gov/pubmed/28250938 http://dx.doi.org/10.1107/S2052252516016675

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