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The Effect of Simulated Flash-Heat Pasteurization on Immune Components of Human Milk
A pasteurization temperature monitoring system has been designed using FoneAstra, a cellphone-based networked sensing system, to monitor simulated flash-heat (FH) pasteurization. This study compared the effect of the FoneAstra FH (F-FH) method with the Sterifeed Holder method currently used by human...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331609/ https://www.ncbi.nlm.nih.gov/pubmed/28241418 http://dx.doi.org/10.3390/nu9020178 |
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author | Daniels, Brodie Schmidt, Stefan King, Tracy Israel-Ballard, Kiersten Amundson Mansen, Kimberly Coutsoudis, Anna |
author_facet | Daniels, Brodie Schmidt, Stefan King, Tracy Israel-Ballard, Kiersten Amundson Mansen, Kimberly Coutsoudis, Anna |
author_sort | Daniels, Brodie |
collection | PubMed |
description | A pasteurization temperature monitoring system has been designed using FoneAstra, a cellphone-based networked sensing system, to monitor simulated flash-heat (FH) pasteurization. This study compared the effect of the FoneAstra FH (F-FH) method with the Sterifeed Holder method currently used by human milk banks on human milk immune components (immunoglobulin A (IgA), lactoferrin activity, lysozyme activity, interleukin (IL)-8 and IL-10). Donor milk samples (N = 50) were obtained from a human milk bank, and pasteurized. Concentrations of IgA, IL-8, IL-10, lysozyme activity and lactoferrin activity were compared to their controls using the Student’s t-test. Both methods demonstrated no destruction of interleukins. While the Holder method retained all lysozyme activity, the F-FH method only retained 78.4% activity (p < 0.0001), and both methods showed a decrease in lactoferrin activity (71.1% Holder vs. 38.6% F-FH; p < 0.0001) and a decrease in the retention of total IgA (78.9% Holder vs. 25.2% F-FH; p < 0.0001). Despite increased destruction of immune components compared to Holder pasteurization, the benefits of F-FH in terms of its low cost, feasibility, safety and retention of immune components make it a valuable resource in low-income countries for pasteurizing human milk, potentially saving infants’ lives. |
format | Online Article Text |
id | pubmed-5331609 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-53316092017-03-13 The Effect of Simulated Flash-Heat Pasteurization on Immune Components of Human Milk Daniels, Brodie Schmidt, Stefan King, Tracy Israel-Ballard, Kiersten Amundson Mansen, Kimberly Coutsoudis, Anna Nutrients Article A pasteurization temperature monitoring system has been designed using FoneAstra, a cellphone-based networked sensing system, to monitor simulated flash-heat (FH) pasteurization. This study compared the effect of the FoneAstra FH (F-FH) method with the Sterifeed Holder method currently used by human milk banks on human milk immune components (immunoglobulin A (IgA), lactoferrin activity, lysozyme activity, interleukin (IL)-8 and IL-10). Donor milk samples (N = 50) were obtained from a human milk bank, and pasteurized. Concentrations of IgA, IL-8, IL-10, lysozyme activity and lactoferrin activity were compared to their controls using the Student’s t-test. Both methods demonstrated no destruction of interleukins. While the Holder method retained all lysozyme activity, the F-FH method only retained 78.4% activity (p < 0.0001), and both methods showed a decrease in lactoferrin activity (71.1% Holder vs. 38.6% F-FH; p < 0.0001) and a decrease in the retention of total IgA (78.9% Holder vs. 25.2% F-FH; p < 0.0001). Despite increased destruction of immune components compared to Holder pasteurization, the benefits of F-FH in terms of its low cost, feasibility, safety and retention of immune components make it a valuable resource in low-income countries for pasteurizing human milk, potentially saving infants’ lives. MDPI 2017-02-22 /pmc/articles/PMC5331609/ /pubmed/28241418 http://dx.doi.org/10.3390/nu9020178 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Daniels, Brodie Schmidt, Stefan King, Tracy Israel-Ballard, Kiersten Amundson Mansen, Kimberly Coutsoudis, Anna The Effect of Simulated Flash-Heat Pasteurization on Immune Components of Human Milk |
title | The Effect of Simulated Flash-Heat Pasteurization on Immune Components of Human Milk |
title_full | The Effect of Simulated Flash-Heat Pasteurization on Immune Components of Human Milk |
title_fullStr | The Effect of Simulated Flash-Heat Pasteurization on Immune Components of Human Milk |
title_full_unstemmed | The Effect of Simulated Flash-Heat Pasteurization on Immune Components of Human Milk |
title_short | The Effect of Simulated Flash-Heat Pasteurization on Immune Components of Human Milk |
title_sort | effect of simulated flash-heat pasteurization on immune components of human milk |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331609/ https://www.ncbi.nlm.nih.gov/pubmed/28241418 http://dx.doi.org/10.3390/nu9020178 |
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