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A hybrid of B and T lymphoblastic cell line could potentially substitute dendritic cells to efficiently expand out Her-2/neu-specific cytotoxic T lymphocytes from advanced breast cancer patients in vitro

Adoptive transfer of cytotoxic T lymphocytes (CTLs) holds promises to cure cancer. However, this treatment is hindered by lacking a robust way to specifically expand out CTLs. Here, we developed a hybrid of B lymphoblastic cell line and T lymphoblastic cell line (T2 cells) as a substitute of dendrit...

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Detalles Bibliográficos
Autores principales: Chen, Sheng, Gu, Feifei, Li, Kang, Zhang, Kai, Liu, Yangyang, Liang, Jinyan, Gao, Wei, Wu, Gang, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331710/
https://www.ncbi.nlm.nih.gov/pubmed/28245833
http://dx.doi.org/10.1186/s13045-017-0429-8