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Development of a surrogate potency assay to determine the angiogenic activity of Stempeucel®, a pooled, ex-vivo expanded, allogeneic human bone marrow mesenchymal stromal cell product

BACKGROUND: Mesenchymal stromal cells (MSCs) have emerged as a more beneficial alternative to conventional therapy and may offer a potential cure for unmet medical needs. MSCs are known to possess strong immunomodulatory and anti-inflammatory properties. Moreover, they promote angiogenesis and tissu...

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Detalles Bibliográficos
Autores principales: Thej, Charan, Ramadasse, Balamurugan, Walvekar, Ankita, Majumdar, Anish S., Balasubramanian, Sudha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331748/
https://www.ncbi.nlm.nih.gov/pubmed/28245882
http://dx.doi.org/10.1186/s13287-017-0488-3