Historical Perspective on Familial Gastric Cancer

Gastric cancer is a common disease worldwide, typically associated with acquired chronic inflammation in the stomach, related in most instances to infection by Helicobacter pylori. A small percentage of cases occurs in familial clusters, and some of these can be linked to specific germline mutations...

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Detalles Bibliográficos
Autores principales: Boland, C. Richard, Yurgelun, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331778/
https://www.ncbi.nlm.nih.gov/pubmed/28275686
http://dx.doi.org/10.1016/j.jcmgh.2016.12.003
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author Boland, C. Richard
Yurgelun, Matthew B.
author_facet Boland, C. Richard
Yurgelun, Matthew B.
author_sort Boland, C. Richard
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description Gastric cancer is a common disease worldwide, typically associated with acquired chronic inflammation in the stomach, related in most instances to infection by Helicobacter pylori. A small percentage of cases occurs in familial clusters, and some of these can be linked to specific germline mutations. This article reviews the historical background to the current understanding of familial gastric cancer, focuses on the entity of hereditary diffuse gastric cancer, and also reviews the risks for gastric cancer related to a number of other familial genetic diseases.
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spelling pubmed-53317782017-03-08 Historical Perspective on Familial Gastric Cancer Boland, C. Richard Yurgelun, Matthew B. Cell Mol Gastroenterol Hepatol Review Gastric cancer is a common disease worldwide, typically associated with acquired chronic inflammation in the stomach, related in most instances to infection by Helicobacter pylori. A small percentage of cases occurs in familial clusters, and some of these can be linked to specific germline mutations. This article reviews the historical background to the current understanding of familial gastric cancer, focuses on the entity of hereditary diffuse gastric cancer, and also reviews the risks for gastric cancer related to a number of other familial genetic diseases. Elsevier 2017-02-28 /pmc/articles/PMC5331778/ /pubmed/28275686 http://dx.doi.org/10.1016/j.jcmgh.2016.12.003 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Boland, C. Richard
Yurgelun, Matthew B.
Historical Perspective on Familial Gastric Cancer
title Historical Perspective on Familial Gastric Cancer
title_full Historical Perspective on Familial Gastric Cancer
title_fullStr Historical Perspective on Familial Gastric Cancer
title_full_unstemmed Historical Perspective on Familial Gastric Cancer
title_short Historical Perspective on Familial Gastric Cancer
title_sort historical perspective on familial gastric cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331778/
https://www.ncbi.nlm.nih.gov/pubmed/28275686
http://dx.doi.org/10.1016/j.jcmgh.2016.12.003
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