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Hedgehog Signaling Links Chronic Inflammation to Gastric Cancer Precursor Lesions

Since its initial discovery in Drosophila, Hedgehog (HH) signaling has long been associated with foregut development. The mammalian genome expresses 3 HH ligands, with sonic hedgehog (SHH) levels highest in the mucosa of the embryonic foregut. More recently, interest in the pathway has shifted to im...

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Detalles Bibliográficos
Autores principales: Merchant, Juanita L., Ding, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331830/
https://www.ncbi.nlm.nih.gov/pubmed/28275687
http://dx.doi.org/10.1016/j.jcmgh.2017.01.004