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Hedgehog Signaling Links Chronic Inflammation to Gastric Cancer Precursor Lesions
Since its initial discovery in Drosophila, Hedgehog (HH) signaling has long been associated with foregut development. The mammalian genome expresses 3 HH ligands, with sonic hedgehog (SHH) levels highest in the mucosa of the embryonic foregut. More recently, interest in the pathway has shifted to im...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331830/ https://www.ncbi.nlm.nih.gov/pubmed/28275687 http://dx.doi.org/10.1016/j.jcmgh.2017.01.004 |