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Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency
The ribosome has been described as a ribozyme in which ribosomal RNA is responsible for peptidyl-transferase reaction catalysis. The W255C mutation of the universally conserved ribosomal protein uL3 has diverse effects on ribosome function (e.g., increased affinities for transfer RNAs, decreased rat...
Autores principales: | Mailliot, Justine, de Loubresse, Nicolas Garreau, Yusupova, Gulnara, Meskauskas, Arturas, Dinman, Jonathan D., Yusupov, Marat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331904/ https://www.ncbi.nlm.nih.gov/pubmed/26906928 http://dx.doi.org/10.1016/j.jmb.2016.02.013 |
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