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Repair of critical sized cranial defects with BMP9-transduced calvarial cells delivered in a thermoresponsive scaffold
Large skeletal defects caused by trauma, congenital malformations, and post-oncologic resections of the calvarium present major challenges to the reconstructive surgeon. We previously identified BMP-9 as the most osteogenic BMP in vitro and in vivo. Here we sought to investigate the bone regenerativ...
Autores principales: | Dumanian, Zari P., Tollemar, Viktor, Ye, Jixing, Lu, Minpeng, Zhu, Yunxiao, Liao, Junyi, Ameer, Guillermo A., He, Tong-Chuan, Reid, Russell R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332017/ https://www.ncbi.nlm.nih.gov/pubmed/28249039 http://dx.doi.org/10.1371/journal.pone.0172327 |
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