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Development of ghrelin resistance in a cancer cachexia rat model using human gastric cancer-derived 85As2 cells and the palliative effects of the Kampo medicine rikkunshito on the model
Cancer cachexia (CC) is a multifactorial disease characterized by decreased food intake and loss of body weight due to reduced musculature with or without loss of fat mass. Patients with gastric cancer have a high incidence of cachexia. We previously established a novel CC rat model induced by human...
Autores principales: | Terawaki, Kiyoshi, Kashiwase, Yohei, Sawada, Yumi, Hashimoto, Hirofumi, Yoshimura, Mitsuhiro, Ohbuchi, Katsuya, Sudo, Yuka, Suzuki, Masami, Miyano, Kanako, Shiraishi, Seiji, Higami, Yoshikazu, Yanagihara, Kazuyoshi, Hattori, Tomohisa, Kase, Yoshio, Ueta, Yoichi, Uezono, Yasuhito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332064/ https://www.ncbi.nlm.nih.gov/pubmed/28249026 http://dx.doi.org/10.1371/journal.pone.0173113 |
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