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Altered regulation and expression of genes by BET family of proteins in COPD patients

BACKGROUND: BET proteins (BRD2, BRD3, BRDT and BRD4) belong to the family of bromodomain containing proteins, which form a class of transcriptional co-regulators. BET proteins bind to acetylated lysine residues in the histones of nucleosomal chromatin and function either as co-activators or co-repre...

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Detalles Bibliográficos
Autores principales:	Malhotra, Rajneesh, Kurian, Nisha, Zhou, Xiao-Hong, Jiang, Fanyi, Monkley, Susan, DeMicco, Amy, Clausen, Ib G., Delgren, Göran, Edenro, Goran, Ahdesmäki, Miika J., Clausen, Maryam, Öberg, Lisa, Israelsson, Elisabeth, Belfield, Graham, Vaarala, Outi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332090/ https://www.ncbi.nlm.nih.gov/pubmed/28248992 http://dx.doi.org/10.1371/journal.pone.0173115

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