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Mechanisms of Vascular Dysfunction in COPD and Effects of a Novel Soluble Epoxide Hydrolase Inhibitor in Smokers

BACKGROUND: Smoking and COPD are risk factors for cardiovascular disease, and the pathogenesis may involve endothelial dysfunction. We tested the hypothesis that endothelium-derived epoxyeicosatrienoic acid (EET)-mediated endothelial function is impaired in patients with COPD and that a novel solubl...

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Detalles Bibliográficos
Autores principales:	Yang, Lucy, Cheriyan, Joseph, Gutterman, David D., Mayer, Ruth J., Ament, Zsuzsanna, Griffin, Jules L., Lazaar, Aili L., Newby, David E., Tal-Singer, Ruth, Wilkinson, Ian B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American College of Chest Physicians 2017
Materias:	Original Research: COPD
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332206/ https://www.ncbi.nlm.nih.gov/pubmed/27884766 http://dx.doi.org/10.1016/j.chest.2016.10.058

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