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Survivin a radiogenetic promoter for glioblastoma viral gene therapy independently from CArG motifs

BACKGROUND: Radiogenetic therapy is a novel approach in the treatment of cancer, which employs genetic modification to alter the sensitivity of tumor cells to the effect of applied radiation. AIM: To select a potent radiation inducible promoter in the context of brain tumors and to investigate if CA...

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Detalles Bibliográficos
Autores principales: Naoum, George E., Zhu, Zeng B., Buchsbaum, Donald J., Curiel, David T., Arafat, Waleed O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332320/
https://www.ncbi.nlm.nih.gov/pubmed/28251571
http://dx.doi.org/10.1186/s40169-017-0140-y

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