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Agglutination by anti-capsular polysaccharide antibody is associated with protection against experimental human pneumococcal carriage
The ability of pneumococcal conjugate vaccine (PCV) to decrease transmission by blocking the acquisition of colonization has been attributed to herd immunity. We describe the role of mucosal IgG to capsular polysaccharide (CPS) in mediating protection from carriage, translating our findings from a m...
Autores principales: | Mitsi, E, Roche, AM, Reiné, J, Zangari, T, Owugha, JT, Pennington, SH, Gritzfeld, JF, Wright, AD, Collins, AM, van Selm, S, de Jonge, MI, Gordon, SB, Weiser, JN, Ferreira, DM |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332540/ https://www.ncbi.nlm.nih.gov/pubmed/27579859 http://dx.doi.org/10.1038/mi.2016.71 |
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