Cargando…

New Evidence for the Theory of Chromosome Organization by Repetitive Elements (CORE)

Repetitive DNA elements were proposed to coordinate chromatin folding and interaction in chromosomes by their intrinsic homology-based clustering ability. A recent analysis of the data sets from chromosome-conformation-capture experiments confirms the spatial clustering of DNA repeats of the same fa...

Descripción completa

Detalles Bibliográficos
Autor principal: Tang, Shao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333070/
https://www.ncbi.nlm.nih.gov/pubmed/28230735
http://dx.doi.org/10.3390/genes8020081
Descripción
Sumario:Repetitive DNA elements were proposed to coordinate chromatin folding and interaction in chromosomes by their intrinsic homology-based clustering ability. A recent analysis of the data sets from chromosome-conformation-capture experiments confirms the spatial clustering of DNA repeats of the same family in the nuclear space, and thus provides strong new support for the CORE theory.