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New Evidence for the Theory of Chromosome Organization by Repetitive Elements (CORE)
Repetitive DNA elements were proposed to coordinate chromatin folding and interaction in chromosomes by their intrinsic homology-based clustering ability. A recent analysis of the data sets from chromosome-conformation-capture experiments confirms the spatial clustering of DNA repeats of the same fa...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333070/ https://www.ncbi.nlm.nih.gov/pubmed/28230735 http://dx.doi.org/10.3390/genes8020081 |
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author | Tang, Shao-Jun |
author_facet | Tang, Shao-Jun |
author_sort | Tang, Shao-Jun |
collection | PubMed |
description | Repetitive DNA elements were proposed to coordinate chromatin folding and interaction in chromosomes by their intrinsic homology-based clustering ability. A recent analysis of the data sets from chromosome-conformation-capture experiments confirms the spatial clustering of DNA repeats of the same family in the nuclear space, and thus provides strong new support for the CORE theory. |
format | Online Article Text |
id | pubmed-5333070 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-53330702017-03-13 New Evidence for the Theory of Chromosome Organization by Repetitive Elements (CORE) Tang, Shao-Jun Genes (Basel) Opinion Repetitive DNA elements were proposed to coordinate chromatin folding and interaction in chromosomes by their intrinsic homology-based clustering ability. A recent analysis of the data sets from chromosome-conformation-capture experiments confirms the spatial clustering of DNA repeats of the same family in the nuclear space, and thus provides strong new support for the CORE theory. MDPI 2017-02-20 /pmc/articles/PMC5333070/ /pubmed/28230735 http://dx.doi.org/10.3390/genes8020081 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Opinion Tang, Shao-Jun New Evidence for the Theory of Chromosome Organization by Repetitive Elements (CORE) |
title | New Evidence for the Theory of Chromosome Organization by Repetitive Elements (CORE) |
title_full | New Evidence for the Theory of Chromosome Organization by Repetitive Elements (CORE) |
title_fullStr | New Evidence for the Theory of Chromosome Organization by Repetitive Elements (CORE) |
title_full_unstemmed | New Evidence for the Theory of Chromosome Organization by Repetitive Elements (CORE) |
title_short | New Evidence for the Theory of Chromosome Organization by Repetitive Elements (CORE) |
title_sort | new evidence for the theory of chromosome organization by repetitive elements (core) |
topic | Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333070/ https://www.ncbi.nlm.nih.gov/pubmed/28230735 http://dx.doi.org/10.3390/genes8020081 |
work_keys_str_mv | AT tangshaojun newevidenceforthetheoryofchromosomeorganizationbyrepetitiveelementscore |