Nicotine facilitates VSMC dysfunction through a miR-200b/RhoGDIA/cytoskeleton module

Nicotine can induce the abnormal migration and proliferation of vascular smooth muscle cells (VSMCs). We have previously shown that cytoskeletal proteins and RhoGDIA, a negative regulator of the Rho GTPase pathway, are involved in the nicotine-induced dysfunction of VSMCs. Here, we found that nicoti...

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Detalles Bibliográficos
Autores principales: Liang, Dongli, Wang, Zhaoxia, Yan, Zhiqiang, Hou, Shangwei, Xu, Wangjie, Wang, Lianyun, Shang, Meisheng, Qiao, Zhongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333142/
https://www.ncbi.nlm.nih.gov/pubmed/28252009
http://dx.doi.org/10.1038/srep43798

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