ddClone: joint statistical inference of clonal populations from single cell and bulk tumour sequencing data

Next-generation sequencing (NGS) of bulk tumour tissue can identify constituent cell populations in cancers and measure their abundance. This requires computational deconvolution of allelic counts from somatic mutations, which may be incapable of fully resolving the underlying population structure....

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Detalles Bibliográficos
Autores principales: Salehi, Sohrab, Steif, Adi, Roth, Andrew, Aparicio, Samuel, Bouchard-Côté, Alexandre, Shah, Sohrab P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333399/
https://www.ncbi.nlm.nih.gov/pubmed/28249593
http://dx.doi.org/10.1186/s13059-017-1169-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333399/
https://www.ncbi.nlm.nih.gov/pubmed/28249593
http://dx.doi.org/10.1186/s13059-017-1169-3

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