Autocatalytic association of proteins by covalent bond formation: a Bio Molecular Welding toolbox derived from a bacterial adhesin

Unusual intramolecular cross-links present in adhesins from Gram-positive bacteria have been used to develop a generic process amenable to biotechnology applications. Based on the crystal structure of RrgA, the Streptococcus pneumoniae pilus adhesin, we provide evidence that two engineered protein f...

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Detalles Bibliográficos
Autores principales: Bonnet, J., Cartannaz, J., Tourcier, G., Contreras-Martel, C., Kleman, J. P., Morlot, C., Vernet, T., Di Guilmi, A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333627/
https://www.ncbi.nlm.nih.gov/pubmed/28252635
http://dx.doi.org/10.1038/srep43564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333627/
https://www.ncbi.nlm.nih.gov/pubmed/28252635
http://dx.doi.org/10.1038/srep43564

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