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Functional analysis of the mammalian RNA ligase for IRE1 in the unfolded protein response

The unfolded protein response (UPR) is a conserved signalling pathway activated on the accumulation of unfolded proteins within the endoplasmic reticulum (ER), termed ER stress. Upon ER stress, HAC1/XBP1 undergoes exon/intron-specific excision by inositol requiring enzyme 1 (IRE1) to remove an intro...

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Detalles Bibliográficos
Autores principales:	Poothong, Juthakorn, Tirasophon, Witoon, Kaufman, Randal J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333776/ https://www.ncbi.nlm.nih.gov/pubmed/28093457 http://dx.doi.org/10.1042/BSR20160574

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