Cargando…

Colon cancer modulation by a diabetic environment: A single institutional experience

BACKGROUND: Multiple observational studies suggest an increased risk of colon cancer in patients with diabetes mellitus (DM). This can theoretically be the result of an influence of the diabetic environment on carcinogenesis or the tumor biologic behavior. AIM: To gain insight into the influence of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prieto, Isabel, del Puerto-Nevado, Laura, Gonzalez, Nieves, Portal-Nuñez, Sergio, Zazo, Sandra, Corton, Marta, Minguez, Pablo, Gomez-Guerrero, Carmen, Arce, Jose Miguel, Sanz, Ana Belen, Mas, Sebastian, Aguilera, Oscar, Alvarez-Llamas, Gloria, Esbrit, Pedro, Ortiz, Alberto, Ayuso, Carmen, Egido, Jesus, Rojo, Federico, Garcia-Foncillas, Jesus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333811/ https://www.ncbi.nlm.nih.gov/pubmed/28253286 http://dx.doi.org/10.1371/journal.pone.0172300

Ejemplares similares

Molecular evidence of field cancerization initiated by diabetes in colon cancer patients
por: Del Puerto‐Nevado, Laura, et al.
Publicado: (2019)

Diabetes‐mediated promotion of colon mucosa carcinogenesis is associated with mitochondrial dysfunction
por: Del Puerto‐Nevado, Laura, et al.
Publicado: (2019)

2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implications
por: González, Nieves, et al.
Publicado: (2017)

Vitamin C uncouples the Warburg metabolic switch in KRAS mutant colon cancer
por: Aguilera, Oscar, et al.
Publicado: (2016)

Effect of bombesin receptor subtype-3 and its synthetic agonist on signaling, glucose transport and metabolism in myocytes from patients with obesity and type 2 diabetes
por: GONZÁLEZ, NIEVES, et al.
Publicado: (2015)

Ras Family of Small GTPases in CRC: New Perspectives for Overcoming Drug Resistance
por: Rio-Vilariño, Anxo, et al.
Publicado: (2021)

Active angiogenesis in metastatic renal cell carcinoma predicts clinical benefit to sunitinib-based therapy
por: del Puerto-Nevado, L, et al.
Publicado: (2014)

Thymidylate synthase expression as a predictive biomarker of pemetrexed sensitivity in advanced non-small cell lung cancer
por: Chamizo, Cristina, et al.
Publicado: (2015)

Vitamin C activates pyruvate dehydrogenase (PDH) targeting the mitochondrial tricarboxylic acid (TCA) cycle in hypoxic KRAS mutant colon cancer
por: Cenigaonandia-Campillo, Aiora, et al.
Publicado: (2021)

Patient Characteristics Associated with Growth of Patient-Derived Tumor Implants in Mice (Patient-Derived Xenografts)
por: Hernández Guerrero, Tatiana, et al.
Publicado: (2023)

Low MicroRNA-19b Expression Shows a Promising Clinical Impact in Locally Advanced Rectal Cancer
por: Rubio, Jaime, et al.
Publicado: (2021)

Validation of microRNA-199b as A Promising Predictor of Outcome and Response to Neoadjuvant Treatment in Locally Advanced Rectal Cancer Patients
por: Cristóbal, Ion, et al.
Publicado: (2021)

MicroRNA-19b Plays a Key Role in 5-Fluorouracil Resistance and Predicts Tumor Progression in Locally Advanced Rectal Cancer Patients
por: Santos, Andrea, et al.
Publicado: (2022)

Minigene Splicing Assays and Long-Read Sequencing to Unravel Pathogenic Deep-Intronic Variants in PAX6 in Congenital Aniridia
por: Tamayo, Alejandra, et al.
Publicado: (2023)

Pathogenic Pathways and Therapeutic Approaches Targeting Inflammation in Diabetic Nephropathy
por: Rayego-Mateos, Sandra, et al.
Publicado: (2020)

Juxtaglomerular apparatus hyperplasia under dual angiotensin blockade. A footprint of adequate RAS inhibition or a concern for renal fibrosis?
por: Fernandez-Fernandez, Beatriz, et al.
Publicado: (2012)

DEK is a potential marker for aggressive phenotype and irinotecan-based therapy response in metastatic colorectal cancer
por: Martinez-Useros, Javier, et al.
Publicado: (2014)

Lipotoxicity and Diabetic Nephropathy: Novel Mechanistic Insights and Therapeutic Opportunities
por: Opazo-Ríos, Lucas, et al.
Publicado: (2020)

Activation of MET pathway predicts poor outcome to cetuximab in patients with recurrent or metastatic head and neck cancer
por: Madoz-Gúrpide, Juan, et al.
Publicado: (2015)

Animal Models of Cardiovascular Diseases
por: Zaragoza, Carlos, et al.
Publicado: (2011)

Improving selection of patients with metastatic colorectal cancer to benefit from cetuximab based on KIR genotypes
por: Manzanares-Martin, Barbara, et al.
Publicado: (2021)

Deregulation of SET is Associated with Tumor Progression and Predicts Adverse Outcome in Patients with Early-Stage Colorectal Cancer
por: Cristóbal, Ion, et al.
Publicado: (2019)

MicroRNA-199b Deregulation Shows a Strong SET-Independent Prognostic Value in Early-Stage Colorectal Cancer
por: Cristóbal, Ion, et al.
Publicado: (2020)

CIP2A as a Key Regulator for AKT Phosphorylation Has Partial Impact Determining Clinical Outcome in Breast Cancer
por: Luque, Melani, et al.
Publicado: (2022)

Hyperlipidemia-Associated Renal Damage Decreases Klotho Expression in Kidneys from ApoE Knockout Mice
por: Sastre, Cristina, et al.
Publicado: (2013)

Expression of Phosphorylated BRD4 Is Markedly Associated with the Activation Status of the PP2A Pathway and Shows a Strong Prognostic Value in Triple Negative Breast Cancer Patients
por: Sanz-Álvarez, Marta, et al.
Publicado: (2021)

The Role of MicroRNAs in Hepatoblastoma Tumors
por: Cristóbal, Ion, et al.
Publicado: (2019)

MicroRNA-199b Downregulation Confers Resistance to 5-Fluorouracil Treatment and Predicts Poor Outcome and Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Patients
por: Cristóbal, Ion, et al.
Publicado: (2020)

SOCS1-Derived Peptide Administered by Eye Drops Prevents Retinal Neuroinflammation and Vascular Leakage in Experimental Diabetes
por: Hernández, Cristina, et al.
Publicado: (2019)

Inflammatory Cytokines and Survival Factors from Serum Modulate Tweak-Induced Apoptosis in PC-3 Prostate Cancer Cells
por: Sanz, Ana Belen, et al.
Publicado: (2012)

Histone lysine crotonylation during acute kidney injury in mice
por: Ruiz-Andres, Olga, et al.
Publicado: (2016)

Prioritization of New Candidate Genes for Rare Genetic Diseases by a Disease-Aware Evaluation of Heterogeneous Molecular Networks
por: de la Fuente, Lorena, et al.
Publicado: (2023)

Long-read genome sequencing identifies cryptic structural variants in congenital aniridia cases
por: Damián, Alejandra, et al.
Publicado: (2023)

Molecular approach in the study of Alström syndrome: Analysis of ten Spanish families
por: Piñeiro-Gallego, Teresa, et al.
Publicado: (2012)

Fcγ receptor activation mediates vascular inflammation and abdominal aortic aneurysm development
por: Lopez‐Sanz, Laura, et al.
Publicado: (2021)

Potential therapeutic value of miR‐425‐5p in metastatic colorectal cancer
por: Cristóbal, Ion, et al.
Publicado: (2016)

VIsoQLR: an interactive tool for the detection, quantification and fine-tuning of isoforms in selected genes using long-read sequencing
por: Núñez-Moreno, Gonzalo, et al.
Publicado: (2023)

Correction: VIsoQLR: an interactive tool for the detection, quantification and fine-tuning of isoforms in selected genes using long-read sequencing
por: Núñez-Moreno, Gonzalo, et al.
Publicado: (2023)

Gene Deficiency in Activating Fcγ Receptors Influences the Macrophage Phenotypic Balance and Reduces Atherosclerosis in Mice
por: Mallavia, Beñat, et al.
Publicado: (2013)

The Hippo Pathway Transducers YAP1/TEAD Induce Acquired Resistance to Trastuzumab in HER2-Positive Breast Cancer
por: González-Alonso, Paula, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_on0vdrq884vb9mdrllp0djf4pd