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Interferon alpha treatment stimulates interferon gamma expression in type I NKT cells and enhances their antiviral effect against hepatitis C virus
Interferon (IFN) inhibits hepatitis C virus (HCV) replication through up-regulation of intrahepatic IFN-stimulated gene expression but also through activation of host immune cells. In the present study, we analyzed the immune cell-mediated antiviral effects of IFN-α using HCV-infected mice. Urokinas...
Autores principales: | Miyaki, Eisuke, Hiraga, Nobuhiko, Imamura, Michio, Uchida, Takuro, Kan, Hiromi, Tsuge, Masataka, Abe-Chayama, Hiromi, Hayes, C. Nelson, Makokha, Grace Naswa, Serikawa, Masahiro, Aikata, Hiroshi, Ochi, Hidenori, Ishida, Yuji, Tateno, Chise, Ohdan, Hideki, Chayama, Kazuaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333814/ https://www.ncbi.nlm.nih.gov/pubmed/28253324 http://dx.doi.org/10.1371/journal.pone.0172412 |
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