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CSB ablation induced apoptosis is mediated by increased endoplasmic reticulum stress response
The DNA repair protein Cockayne syndrome group B (CSB) has been recently identified as a promising anticancer target. Suppression, by antisense technology, of this protein causes devastating effects on tumor cells viability, through a massive induction of apoptosis, while being non-toxic to non-tran...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333825/ https://www.ncbi.nlm.nih.gov/pubmed/28253359 http://dx.doi.org/10.1371/journal.pone.0172399 |