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Age-related changes in CD4(+)CD25(+)FOXP3(+) regulatory T cells and their relationship with lung cancer
OBJECTIVES: CD4(+)CD25(+)FOXP3(+) regulatory T cells (Treg) inhibit the anti-tumour immune response and reduce the effect of cancer immunotherapy. Although studies have demonstrated that the number and suppressive activity of Treg increase with age, it is not clear whether these changes correlate wi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333862/ https://www.ncbi.nlm.nih.gov/pubmed/28253320 http://dx.doi.org/10.1371/journal.pone.0173048 |