DNA repair and replication links to pluripotency and differentiation capacity of pig iPS cells

Pigs are proposed to be suitable large animal models for test of the efficacy and safety of induced pluripotent stem cells (iPSCs) for stem cell therapy, but authentic pig ES/iPS cell lines with germline competence are rarely produced. The pathways or signaling underlying the defective competent pig...

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Detalles Bibliográficos
Autores principales: Liu, Kai, Mao, Jian, Song, Lipu, Fan, Anran, Zhang, Sheng, Wang, Jianyu, Fan, Nana, Liu, Na, Ye, Xiaoying, Fu, Haifeng, Zhou, Zhongcheng, Wang, Yong, Wei, Hong, Liu, Zhonghua, Li, Ziyi, Lai, Liangxue, Wang, Xumin, Liu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333863/
https://www.ncbi.nlm.nih.gov/pubmed/28253351
http://dx.doi.org/10.1371/journal.pone.0173047

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