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New Aging Index Using Signal Features of Both Photoplethysmograms and Acceleration Plethysmograms
OBJECTIVES: Acceleration plethysmograms (APGs) are obtained by taking the second derivative of photoplethysmograms (PPGs) and are noninvasive circulatory signals related to risk factors for atherosclerosis with age. There has been growing interest in the development of mobile devices to collect and...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Korean Society of Medical Informatics
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334132/ https://www.ncbi.nlm.nih.gov/pubmed/28261531 http://dx.doi.org/10.4258/hir.2017.23.1.53 |
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author | Ahn, Jae Mok |
author_facet | Ahn, Jae Mok |
author_sort | Ahn, Jae Mok |
collection | PubMed |
description | OBJECTIVES: Acceleration plethysmograms (APGs) are obtained by taking the second derivative of photoplethysmograms (PPGs) and are noninvasive circulatory signals related to risk factors for atherosclerosis with age. There has been growing interest in the development of mobile devices to collect and analyze PPG single features for ambulatory health monitoring. The present study aimed to extract a new feature from the morphologies of APG and PPG signals to classify the dominant indices related to the pulsatile volume of blood in tissue according to age. METHODS: Ten APG and 14 PPG indices were simultaneously extracted. All indices were compared via Pearson correlation coefficients (r) and a regression analysis. We introduced a combined index extracted from both the PPG and APG indices defined as the inflection point area plus the d_peak (IPAD). The participants included 93 healthy adults aged 36–86 years with a mean ± standard deviation age of 57.43 ± 11.99 years. RESULTS: The d_peak and age index for the APG indices were significantly correlated with age (r = −0.408, p < 0.0001 and r = 0.296, p = 0.0039, respectively). Only the A1 time for PPG indices was moderately correlated with age (r = −0.247, p = 0.017). The stiffness index, including individual height information, was not related to age (r = −0.031, p = 0.7713). However, the combined IPAD index was significantly more correlated with age (r = 0.56, p < 0.001) than the other indices. CONCLUSIONS: The proposed index outperformed the other 24 indices for evaluating vascular aging. We suggest that the IPAD is a significant factor related to the clinical information embedded in the PPG waveform. |
format | Online Article Text |
id | pubmed-5334132 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Korean Society of Medical Informatics |
record_format | MEDLINE/PubMed |
spelling | pubmed-53341322017-03-03 New Aging Index Using Signal Features of Both Photoplethysmograms and Acceleration Plethysmograms Ahn, Jae Mok Healthc Inform Res Original Article OBJECTIVES: Acceleration plethysmograms (APGs) are obtained by taking the second derivative of photoplethysmograms (PPGs) and are noninvasive circulatory signals related to risk factors for atherosclerosis with age. There has been growing interest in the development of mobile devices to collect and analyze PPG single features for ambulatory health monitoring. The present study aimed to extract a new feature from the morphologies of APG and PPG signals to classify the dominant indices related to the pulsatile volume of blood in tissue according to age. METHODS: Ten APG and 14 PPG indices were simultaneously extracted. All indices were compared via Pearson correlation coefficients (r) and a regression analysis. We introduced a combined index extracted from both the PPG and APG indices defined as the inflection point area plus the d_peak (IPAD). The participants included 93 healthy adults aged 36–86 years with a mean ± standard deviation age of 57.43 ± 11.99 years. RESULTS: The d_peak and age index for the APG indices were significantly correlated with age (r = −0.408, p < 0.0001 and r = 0.296, p = 0.0039, respectively). Only the A1 time for PPG indices was moderately correlated with age (r = −0.247, p = 0.017). The stiffness index, including individual height information, was not related to age (r = −0.031, p = 0.7713). However, the combined IPAD index was significantly more correlated with age (r = 0.56, p < 0.001) than the other indices. CONCLUSIONS: The proposed index outperformed the other 24 indices for evaluating vascular aging. We suggest that the IPAD is a significant factor related to the clinical information embedded in the PPG waveform. Korean Society of Medical Informatics 2017-01 2017-01-31 /pmc/articles/PMC5334132/ /pubmed/28261531 http://dx.doi.org/10.4258/hir.2017.23.1.53 Text en © 2017 The Korean Society of Medical Informatics http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Ahn, Jae Mok New Aging Index Using Signal Features of Both Photoplethysmograms and Acceleration Plethysmograms |
title | New Aging Index Using Signal Features of Both Photoplethysmograms and Acceleration Plethysmograms |
title_full | New Aging Index Using Signal Features of Both Photoplethysmograms and Acceleration Plethysmograms |
title_fullStr | New Aging Index Using Signal Features of Both Photoplethysmograms and Acceleration Plethysmograms |
title_full_unstemmed | New Aging Index Using Signal Features of Both Photoplethysmograms and Acceleration Plethysmograms |
title_short | New Aging Index Using Signal Features of Both Photoplethysmograms and Acceleration Plethysmograms |
title_sort | new aging index using signal features of both photoplethysmograms and acceleration plethysmograms |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334132/ https://www.ncbi.nlm.nih.gov/pubmed/28261531 http://dx.doi.org/10.4258/hir.2017.23.1.53 |
work_keys_str_mv | AT ahnjaemok newagingindexusingsignalfeaturesofbothphotoplethysmogramsandaccelerationplethysmograms |