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Modeling and optimization of nanoemulsion containing Sorafenib for cancer treatment by response surface methodology
The aim of this study is the development of nanoemulsions for intravenous administration of Sorafenib, which is a poorly soluble drug with no parenteral treatment. The formulation was prepared by a high energy emulsification method and optimized by response surface methodology. The effects of overhe...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334191/ https://www.ncbi.nlm.nih.gov/pubmed/28293282 http://dx.doi.org/10.1186/s13065-017-0248-6 |