Cargando…

Cancer cell chemokines direct chemotaxis of activated stellate cells in pancreatic ductal adenocarcinoma

The mechanisms by which the extreme desmoplasia observed in pancreatic tumors develops remain unknown and its role in pancreatic cancer progression is unsettled. Chemokines play a key role in the recruitment of a wide variety of cell types in health and disease. Transcript and protein profile analys...

Descripción completa

Detalles Bibliográficos
Autores principales:	Roy, Ishan, Boyle, Kathleen A., Vonderhaar, Emily P., Zimmerman, Noah P., Gorse, Egal, Mackinnon, A. Craig, Hwang, Rosa, Franco-Barraza, Janusz, Cukierman, Edna, Tsai, Susan, Evans, Douglas B., Dwinell, Michael B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334280/ https://www.ncbi.nlm.nih.gov/pubmed/28092365 http://dx.doi.org/10.1038/labinvest.2016.146

Ejemplares similares

CXCL12 Chemokine Expression Suppresses Human Pancreatic Cancer Growth and Metastasis
por: Roy, Ishan, et al.
Publicado: (2014)

Chemokine receptors and T cell chemotaxis
Publicado: (1996)

2543 High concentrations of CXCL12 decrease pancreatic adenocarcinoma growth
por: Vonderhaar, Emily, et al.
Publicado: (2018)

Targeted Intestinal Epithelial Deletion of the Chemokine Receptor CXCR4 Reveals Key Roles for Extracellular-Regulated Kinase-1/2 in Restitution
por: Zimmerman, Noah P., et al.
Publicado: (2011)

Targeted immune activation in pediatric solid tumors: opportunities to complement local control approaches
por: Vonderhaar, Emily P., et al.
Publicado: (2023)

Chemokines in the corpus luteum: Implications of leukocyte chemotaxis
por: Townson, David H, et al.
Publicado: (2003)

Negative regulation of chemokine receptor signaling and B-cell chemotaxis by p66Shc
por: Patrussi, L, et al.
Publicado: (2014)

The Role of Stellate Cells in Pancreatic Ductal Adenocarcinoma: Targeting Perspectives
por: Wu, Yang, et al.
Publicado: (2021)

Gamma-delta T cells stimulate IL-6 production by pancreatic stellate cells in pancreatic ductal adenocarcinoma
por: Seifert, Adrian M., et al.
Publicado: (2020)

Subtypes of pancreatic stellate cells and distant metastasis of pancreatic ductal adenocarcinoma
por: Fan, Yuhui, et al.
Publicado: (2020)

Polarization of Chemokine Receptors to the Leading Edge during Lymphocyte Chemotaxis
por: Nieto, Marta, et al.
Publicado: (1997)

FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells
por: Lee, Hyung-Ok, et al.
Publicado: (2011)

Influence of SPIO labelling on the function of BMSCs in chemokine receptors expression and chemotaxis
por: Liu, Yuanchun, et al.
Publicado: (2023)

CXCL12 Chemokine Expression and Secretion Regulates Colorectal Carcinoma Cell Anoikis through Bim-Mediated Intrinsic Apoptosis
por: Drury, Luke J., et al.
Publicado: (2010)

Pancreatic stellate cells regulate blood vessel density in the stroma of pancreatic ductal adenocarcinoma
por: Di Maggio, Francesco, et al.
Publicado: (2016)

Functions of pancreatic stellate cell-derived soluble factors in the microenvironment of pancreatic ductal carcinoma
por: Wu, Qi, et al.
Publicado: (2017)

Diabetes in Humans Activates Pancreatic Stellate Cells via RAGE in Pancreatic Ductal Adenocarcinoma
por: Uchida, Chiaki, et al.
Publicado: (2021)

Chemokines in and out of the central nervous system: much more than chemotaxis and inflammation
por: Cardona, Astrid E, et al.
Publicado: (2008)

Force-exerting perpendicular lateral protrusions in fibroblastic cell contraction
por: Padhi, Abinash, et al.
Publicado: (2020)

Author Correction: Force-exerting perpendicular lateral protrusions in fibroblastic cell contraction
por: Padhi, Abinash, et al.
Publicado: (2020)

CD38 in cancer-associated fibroblasts promotes pro-tumoral activity
por: Ben Baruch, Bar, et al.
Publicado: (2020)

CHEMOTAXIS OF MONONUCLEAR CELLS
por: Ward, Peter A.
Publicado: (1968)

Regulation of T cell chemotaxis by CXCL4
por: Woller, G, et al.
Publicado: (2009)

Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis
por: Morvaridi, Susan, et al.
Publicado: (2015)

BAG3‐positive pancreatic stellate cells promote migration and invasion of pancreatic ductal adenocarcinoma
por: Yuan, Ye, et al.
Publicado: (2019)

Therapeutic T cells induce tumor-directed chemotaxis of innate immune cells through tumor-specific secretion of chemokines and stimulation of B16BL6 melanoma to secrete chemokines
por: Winter, Hauke, et al.
Publicado: (2007)

Contrasting in vitro vs. in vivo effects of a cell membrane-specific CC-chemokine binding protein on macrophage chemotaxis
por: McNeill, Eileen, et al.
Publicado: (2014)

Drosophila blood cell chemotaxis()
por: Evans, Iwan Robert, et al.
Publicado: (2014)

A Novel Mechanism of Soluble HLA-G Mediated Immune Modulation: Downregulation of T Cell Chemokine Receptor Expression and Impairment of Chemotaxis
por: Morandi, Fabio, et al.
Publicado: (2010)

Anti-HIV Agent Trichosanthin Enhances the Capabilities of Chemokines to Stimulate Chemotaxis and G Protein Activation, and This Is Mediated through Interaction of Trichosanthin and Chemokine Receptors
por: Zhao, Jian, et al.
Publicado: (1999)

Targeting chemokines/chemokine receptors: a promising strategy for enhancing the immunotherapy of pancreatic ductal adenocarcinoma
por: Gong, Ruining, et al.
Publicado: (2020)

The critical roles of activated stellate cells-mediated paracrine signaling, metabolism and onco-immunology in pancreatic ductal adenocarcinoma
por: Fu, Yaojie, et al.
Publicado: (2018)

In vitro chemokine (C-C motif) receptor 6-dependent non-inflammatory chemotaxis during spermatogenesis
por: Diao, Ruiying, et al.
Publicado: (2018)

ADP secreted by dying melanoma cells mediates chemotaxis and chemokine secretion of macrophages via the purinergic receptor P2Y12
por: Kloss, Loreen, et al.
Publicado: (2019)

Interleukin-17 (IL-17) Expression Is Reduced during Acute Myocardial Infarction: Role on Chemokine Receptor Expression in Monocytes and Their in Vitro Chemotaxis towards Chemokines
por: Troitskaya, Maria, et al.
Publicado: (2012)

Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia()
por: Pitarresi, Jason R., et al.
Publicado: (2016)

Hepatic Stellate Cells and Hepatocarcinogenesis
por: Barry, Anna E., et al.
Publicado: (2020)

One cell, two chemotaxis systems
por: Tuma, Rabiya S.
Publicado: (2006)

Bleb-driven chemotaxis of Dictyostelium cells
por: Zatulovskiy, Evgeny, et al.
Publicado: (2014)

Enhancing T Cell Chemotaxis and Infiltration in Glioblastoma
por: Singh, Kirit, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_cpss35fnqq37aojqvvebchvl2q