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Glucose‐ or insulin resistance‐mediated β‐cell replication: PKCζ integrates the proliferative signaling
Glucose‐ or insulin resistance‐mediated β‐cell replication serves as a useful physiological model of β‐cell mass expansion to study the pathophysiology of type 2 diabetes. Lakshmipathi et al. (2016) report that PKCζ activation is crucial for compensatory β‐cell proliferation induced by glucose stimu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334311/ https://www.ncbi.nlm.nih.gov/pubmed/27479547 http://dx.doi.org/10.1111/jdi.12558 |