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Cereblon and IRF4 Variants Affect Risk and Response to Treatment in Multiple Myeloma
Multiple myeloma (MM) is a plasma-cell malignancy derived from an early precursor of the B-cell lineage characterised by bone-marrow infiltration, lytic bone lesions, and the presence of a monoclonal protein in serum and/or urine. Interferon regulatory factor 4 (IRF4) is a critical transcriptional r...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334380/ https://www.ncbi.nlm.nih.gov/pubmed/28083618 http://dx.doi.org/10.1007/s00005-016-0442-6 |