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Cereblon and IRF4 Variants Affect Risk and Response to Treatment in Multiple Myeloma

Multiple myeloma (MM) is a plasma-cell malignancy derived from an early precursor of the B-cell lineage characterised by bone-marrow infiltration, lytic bone lesions, and the presence of a monoclonal protein in serum and/or urine. Interferon regulatory factor 4 (IRF4) is a critical transcriptional r...

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Detalles Bibliográficos
Autores principales: Butrym, Aleksandra, Łacina, Piotr, Rybka, Justyna, Chaszczewska-Markowska, Monika, Mazur, Grzegorz, Bogunia-Kubik, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334380/
https://www.ncbi.nlm.nih.gov/pubmed/28083618
http://dx.doi.org/10.1007/s00005-016-0442-6