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A novel, potentially targetable TMEM106B-BRAF fusion in pleomorphic xanthoastrocytoma

Pleomorphic xanthoastrocytoma (PXA) is a World Health Organization (WHO) Grade II glioma occurring primarily in children and young adults. Most PXAs harbor the known activating mutation BRAF V600E. We report a case of locally recurrent PXA with anaplastic features in a 10-yr-old female. The PXA was...

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Detalles Bibliográficos
Autores principales:	Hsiao, Susan J., Karajannis, Matthias A., Diolaiti, Daniel, Mansukhani, Mahesh M., Bender, Julia Glade, Kung, Andrew L., Garvin, James H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Rapid Cancer Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334470/ https://www.ncbi.nlm.nih.gov/pubmed/28299358 http://dx.doi.org/10.1101/mcs.a001396

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