Neuropeptide Y resists excess loss of fat by lipolysis in calorie‐restricted mice: a trait potential for the life‐extending effect of calorie restriction

Neuropeptide Y (NPY) is an orexigenic peptide that plays an essential role in caloric restriction (CR)‐mediated lifespan extension. However, the mechanisms underlying the NPY‐mediated effects in CR are poorly defined. Here, we report that NPY deficiency in male mice during CR increases mortality in...

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Detalles Bibliográficos
Autores principales: Park, Seongjoon, Komatsu, Toshimitsu, Kim, Sang Eun, Tanaka, Katsuya, Hayashi, Hiroko, Mori, Ryoichi, Shimokawa, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334538/
https://www.ncbi.nlm.nih.gov/pubmed/28101970
http://dx.doi.org/10.1111/acel.12558

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