Metabolic Profiling as a Screening Tool for Cytotoxic Compounds: Identification of 3-Alkyl Pyridine Alkaloids from Sponges Collected at a Shallow Water Hydrothermal Vent Site North of Iceland

Twenty-eight sponge specimens were collected at a shallow water hydrothermal vent site north of Iceland. Extracts were prepared and tested in vitro for cytotoxic activity, and eight of them were shown to be cytotoxic. A mass spectrometry (MS)-based metabolomics approach was used to determine the che...

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Detalles Bibliográficos
Autores principales: Einarsdottir, Eydis, Magnusdottir, Manuela, Astarita, Giuseppe, Köck, Matthias, Ögmundsdottir, Helga M., Thorsteinsdottir, Margret, Rapp, Hans Tore, Omarsdottir, Sesselja, Paglia, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334632/
https://www.ncbi.nlm.nih.gov/pubmed/28241423
http://dx.doi.org/10.3390/md15020052

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