Promoting in vivo remyelination with small molecules: a neuroreparative pharmacological treatment for Multiple Sclerosis

Multiple Sclerosis (MS) is a neurodegenerative disease where immune-driven demyelination occurs with inefficient remyelination, but therapies are limited, especially those to enhance repair. Here, we show that the dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, VP3.15, a he...

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Detalles Bibliográficos
Autores principales: Medina-Rodríguez, Eva María, Bribián, Ana, Boyd, Amanda, Palomo, Valle, Pastor, Jesús, Lagares, Alfonso, Gil, Carmen, Martínez, Ana, Williams, Anna, de Castro, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335257/
https://www.ncbi.nlm.nih.gov/pubmed/28256546
http://dx.doi.org/10.1038/srep43545

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