A Core Regulatory Circuit in Glioblastoma Stem Cells Links MAPK Activation to a Transcriptional Program of Neural Stem Cell Identity

Glioblastoma, the most common primary malignant brain tumor, harbors a small population of tumor initiating cells (glioblastoma stem cells) that have many properties similar to neural stem cells. To investigate common regulatory networks in both neural and glioblastoma stem cells, we subjected both...

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Detalles Bibliográficos
Autores principales: Riddick, Gregory, Kotliarova, Svetlana, Rodriguez, Virginia, Kim, H. S., Linkous, Amanda, Storaska, Andrew J., Ahn, Susie, Walling, Jennifer, Belova, Galina, Fine, Howard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335262/
https://www.ncbi.nlm.nih.gov/pubmed/28256619
http://dx.doi.org/10.1038/srep43605

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