An inflammatory gene signature distinguishes neurofibroma Schwann cells and macrophages from cells in the normal peripheral nervous system

Neurofibromas are benign peripheral nerve tumors driven by NF1 loss in Schwann cells (SCs). Macrophages are abundant in neurofibromas, and macrophage targeted interventions may have therapeutic potential in these tumors. We generated gene expression data from fluorescence-activated cell sorted (FACS...

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Detalles Bibliográficos
Autores principales: Choi, Kwangmin, Komurov, Kakajan, Fletcher, Jonathan S., Jousma, Edwin, Cancelas, Jose A., Wu, Jianqiang, Ratner, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335359/
https://www.ncbi.nlm.nih.gov/pubmed/28256556
http://dx.doi.org/10.1038/srep43315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335359/
https://www.ncbi.nlm.nih.gov/pubmed/28256556
http://dx.doi.org/10.1038/srep43315

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