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INPP5E Preserves Genomic Stability through Regulation of Mitosis

The partially understood phosphoinositide signaling cascade regulates multiple aspects of cellular metabolism. Previous studies revealed that INPP5E, the inositol polyphosphate-5-phosphatase that is mutated in the developmental disorders Joubert and MORM syndromes, is essential for the function of t...

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Detalles Bibliográficos
Autores principales: Sierra Potchanant, Elizabeth A., Cerabona, Donna, Sater, Zahi Abdul, He, Ying, Sun, Zejin, Gehlhausen, Jeff, Nalepa, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335510/
https://www.ncbi.nlm.nih.gov/pubmed/28031327
http://dx.doi.org/10.1128/MCB.00500-16