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INPP5E Preserves Genomic Stability through Regulation of Mitosis
The partially understood phosphoinositide signaling cascade regulates multiple aspects of cellular metabolism. Previous studies revealed that INPP5E, the inositol polyphosphate-5-phosphatase that is mutated in the developmental disorders Joubert and MORM syndromes, is essential for the function of t...
Autores principales: | Sierra Potchanant, Elizabeth A., Cerabona, Donna, Sater, Zahi Abdul, He, Ying, Sun, Zejin, Gehlhausen, Jeff, Nalepa, Grzegorz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335510/ https://www.ncbi.nlm.nih.gov/pubmed/28031327 http://dx.doi.org/10.1128/MCB.00500-16 |
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