Proline dehydrogenase from Thermus thermophilus does not discriminate between FAD and FMN as cofactor

Flavoenzymes are versatile biocatalysts containing either FAD or FMN as cofactor. FAD often binds to a Rossmann fold, while FMN prefers a TIM-barrel or flavodoxin-like fold. Proline dehydrogenase is denoted as an exception: it possesses a TIM barrel-like fold while binding FAD. Using a riboflavin au...

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Detalles Bibliográficos
Autores principales: Huijbers, Mieke M. E., Martínez-Júlvez, Marta, Westphal, Adrie H., Delgado-Arciniega, Estela, Medina, Milagros, van Berkel, Willem J. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335563/
https://www.ncbi.nlm.nih.gov/pubmed/28256579
http://dx.doi.org/10.1038/srep43880

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